TRIM29 (Lung Squamous Cell Carcinoma Marker) Antibody, IgG2b, Clone: [TRIM29/1042], Mouse, Monoclonal

Catalog Number: NBT-23650-MSM2-P1
Article Name: TRIM29 (Lung Squamous Cell Carcinoma Marker) Antibody, IgG2b, Clone: [TRIM29/1042], Mouse, Monoclonal
Biozol Catalog Number: NBT-23650-MSM2-P1
Supplier Catalog Number: 23650-MSM2-P1
Alternative Catalog Number: NBT-23650-MSM2-P1-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: WB
Species Reactivity: Human
Immunogen: Recombinant fragment (126 Amino acid residues between aa 1-200) of human TRIM29 protein
Alternative Names: Ataxia telangiectasia group D complementing gene (ATDC), Tripartite motif-containing protein 29 (TRIM29),
It recognizes a 66kDa protein, which is identified as Tripartite motif-containing protein 29 (TRIM29). It interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA. High expression of TRIM29 has been reported in gastric cancer and pancreatic cancer, and correlates with enhanced tumor growth and lymph node metastasis. TRIM29 is also able to distinguish lung squamous cell carcinoma from lung adenocarcinoma with ~90% positive accuracy, when used in a panel with TTF-1, p63, CK5/6, and Napsin-A antibodies.
Clonality: Monoclonal
Clone Designation: [TRIM29/1042]
Molecular Weight: 66kDa
Isotype: IgG2b
NCBI: 23650
UniProt: Q14134
Form: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Western Blot Analysis of TRIM29 Recombinant protein fragment & A431 cell lysate TRIM29 Monoclonal Antibody (TRIM29/1042).
SDS-PAGE Analysis of Purified TRIM29 Monoclonal Antibody (TRIM29/1042). Confirmation of Purity and Integrity of Antibody.