GCHFR Antibody, IgG2, Clone: [GCHFR/7731], Mouse, Monoclonal

Catalog Number: NBT-2644-MSM1-P1ABX
Article Name: GCHFR Antibody, IgG2, Clone: [GCHFR/7731], Mouse, Monoclonal
Biozol Catalog Number: NBT-2644-MSM1-P1ABX
Supplier Catalog Number: 2644-MSM1-P1ABX
Alternative Catalog Number: NBT-2644-MSM1-P1ABX-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant fragment human GCHFR protein (exact sequence is proprietary)
Alternative Names: GTP Cyclohydrolase I Feedback Regulatory Protein, GTP Cyclohydrolase I Feedback Regulator, GFRP, p35
GTP cyclohydrolase I feedback regulatory protein (GFRP) is encoded by the gene GCHFR. GFRP mediates feedback inhibition of GTP cyclohydrolase I activity by tetrahydrobiopterin. GFRP also acts as a mediator for the stimulatory effect of phenylalanine on enzyme activity. L-phenylalanine reverses this inhibition. Cross-linking experiments have shown that GFRP is usually expressed as a homodimer or pentamer.
Clonality: Monoclonal
Clone Designation: [GCHFR/7731]
Molecular Weight: 63kDa
Isotype: IgG2
NCBI: 2644
UniProt: P30047
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified GCHFR Mouse Monoclonal Antibody (GCHFR/7731). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human liver in HCC stained with GCHFR Mouse Monoclonal Antibody (GCHFR/7731). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.