Tenascin C (Stromal Marker for Epithelial Malignancy) Antibody, IgG1, Clone: [SPM319], Mouse, Monoclonal
Biozol Catalog Number:
NBT-3371-MSM1X-P1ABX
Supplier Catalog Number:
3371-MSM1X-P1ABX
Alternative Catalog Number:
NBT-3371-MSM1X-P1ABX-100
Manufacturer:
NeoBiotechnologies
Host:
Mouse
Category:
Antikörper
Application:
FC, IF, IHC
Species Reactivity:
Human
Immunogen:
Human breast carcinoma
Alternative Names:
Cytotactin, Glioma-associated-extracellular matrix antigen, GMEM, GP 150-225, Hexabrachion (HXB), JI, Myotendinous antigen, Neuronectin, TNC
In Western blotting, it reacts with two bands of ~MW of 210kDa and 300kDa, identified as two isoforms of Tenascin C. Specificity of this MAb is validated by sequential immunoprecipitation with a PAb against Tenascin C. Tenascin C is a multifunctional, disulfide-linkedhexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), ,Immunohistochemistry (Formalin-fixed) (2-4ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 mi
SDS-PAGE Analysis of Purified Tenascin C Mouse Monoclonal Antibody (SPM319). Confirmation of Integrity and Purity of Antibody.
Formalin-fixed, paraffin-embedded human Lung Carcinoma stained with Tenascin C Mouse Monoclonal Antibody (SPM319).
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