Recognizes a protein of 20-25kDa, identified as human interferon. This MAb is specific to human IFN-A and recognizes both recombinant and native human IFN-gamma. T lymphocytes and NK cells mainly produce IFN-A. It is a pleiotropic cytokine involved in the regulation of nearly all phases of immune and inflammatory responses, including the activation, growth and differentiation of T cell, B cells, macrophages, NK cells and other cell types such as endothelial cells and fibroblasts. It has weak anti-viral and anti-proliferative activity, and potentiates the antiviral and anti-tumor effects of IFN-(TM)/A°a (type I interferon).
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilutio
Formalin-fixed, paraffin-embedded human kidney stained with Interferon gamma Recombinant Rabbit Monoclonal Antibody (IFNG/3996R).
Formalin-fixed, paraffin-embedded human kidney stained with Interferon gamma Recombinant Rabbit Monoclonal Antibody (IFNG/3996R).
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