Interleukin-2 (IL-2) Antibody, IgG1, Clone: [IL2/8712], Mouse, Monoclonal

Catalog Number: NBT-3558-MSM14-P1
Article Name: Interleukin-2 (IL-2) Antibody, IgG1, Clone: [IL2/8712], Mouse, Monoclonal
Biozol Catalog Number: NBT-3558-MSM14-P1
Supplier Catalog Number: 3558-MSM14-P1
Alternative Catalog Number: NBT-3558-MSM14-P1-100
Manufacturer: NeoBiotechnologies
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant fragment (around aa1-153) of human IL2 protein (exact sequence is proprietary)
Alternative Names: Aldesleukin, Involved in regulation of T cell clonal expansion, Lymphokine, POIL2, T-cell growth factor (TCGF)
Interleukin-2 (IL-2) is a T cell stimulatory cytokine that induces T cell proliferation and NK cell proliferation and activation. Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). IL-2 induces CTLA-4 and also functions as a survival factor for lymphocytes.
Clonality: Monoclonal
Clone Designation: [IL2/8712]
Molecular Weight: 15kDa
Isotype: IgG1
NCBI: 3558
UniProt: P60568
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified Interleukin-2 (IL-2) Mouse Monoclonal Antibody (IL2/8712). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human adrenal gland stained with Purified Interleukin-2 (IL-2) Mouse Monoclonal Antibody (IL2/8712). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.