Insulin / IRDN (beta-Cell & Insulinoma Marker) Antibody, IgG1, Clone: [E2-E3+2D11-H5, same as INS04+INS05], Mouse, Monoclonal
Biozol Catalog Number:
NBT-3630-MSM3-P1ABX
Supplier Catalog Number:
3630-MSM3-P1ABX
Alternative Catalog Number:
NBT-3630-MSM3-P1ABX-100
Manufacturer:
NeoBiotechnologies
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Bovine, Human, Mouse, Porcine, Rabbit
Immunogen:
Purified pig insulin, conjugated to KLH (E2-E3 & 2D11-H5)
Alternative Names:
IDDM2, ILPR, IRDN, MODY10, Proinsulin
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Application Notes:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes), Optimal dilution f
Formalin-fixed, paraffin-embedded human Pancreas stained with Insulin Mouse Monoclonal Antibody (E2-E3+2D11-H5).
SDS-PAGE Analysis of Purified Insulin Mouse Monoclonal Antibody (E2-E3+2D11-H5). Confirmation of Integrity and Purity of Antibody
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