Recombinant CD103 / Integrin alphaEbeta7 (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody, Clone: [ITGAE/3904R], Rabbit, Monoclonal

Catalog Number: NBT-3682-RBM6-P1
Article Name: Recombinant CD103 / Integrin alphaEbeta7 (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody, Clone: [ITGAE/3904R], Rabbit, Monoclonal
Biozol Catalog Number: NBT-3682-RBM6-P1
Supplier Catalog Number: 3682-RBM6-P1
Alternative Catalog Number: NBT-3682-RBM6-P1-100
Manufacturer: NeoBiotechnologies
Host: Rabbit
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant human ITGAE/CD103 protein fragment (aa 775-855) (exact sequence is proprietary)
Alternative Names: CD103, Human mucosal lymphocyte antigen 1 (HML1 antigen), Integrin alpha E heavy chain, Integrin alpha E light chain, Integrin alpha E, epithelial-associated, Integrin alpha E1, Integrin alpha-IEL (intestinal intraepithelial lymphocytes), Integrin alpha M290, Integrin alpha-E heavy chain, Integrin, alpha E (ITGAE)
This MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).
Clonality: Monoclonal
Clone Designation: [ITGAE/3904R]
Molecular Weight: 150kDa
NCBI: 3682
UniProt: P38570
Form: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human Tonsil stained with CD103 Recombinant Rabbit Monoclonal Antibody (ITGAE/3904R).
SDS-PAGE Analysis Purified CD103 Recombinant Rabbit Monoclonal Antibody (ITGAE/3904R). Confirmation of Purity and Integrity of Antibody.