Recombinant TACSTD2 / TROP2 (Epithelial Marker) Antibody, IgG1, Clone: [rTACSTD2/6395], Mouse, Monoclonal

Article Name:	Recombinant TACSTD2 / TROP2 (Epithelial Marker) Antibody, IgG1, Clone: [rTACSTD2/6395], Mouse, Monoclonal
Biozol Catalog Number:	NBT-4070-MSM5-P0
Supplier Catalog Number:	4070-MSM5-P0
Alternative Catalog Number:	NBT-4070-MSM5-P0-20,NBT-4070-MSM5-P0-100
Manufacturer:	NeoBiotechnologies
Host:	Mouse
Category:	Antikörper
Application:	IHC, WB
Species Reactivity:	Hamster, Human, Mouse, Rat
Immunogen:	Recombinant fragment of human TACSTD2 protein (around aa 31-274) (exact sequence is proprietary)
Alternative Names:	Cell surface glycoprotein Trop-2, Membrane Component Chromosome 1, Surface Marker 1 (M1S1), Pancreatic Carcinoma Marker Protein GA733-1, TROP2, Tumor-Associated Calcium Signal Transducer 2 (TACSTD2)

TACSTD2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

Clonality:	Monoclonal
Clone Designation:	[rTACSTD2/6395]
Molecular Weight:	40kDa
Isotype:	IgG1
NCBI:	4070
UniProt:	P09758
Form:	200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:	Recombinant Monoclonal Antibody

Application Notes:

Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti


	Formalin-fixed, paraffin-embedded human colon carcinoma stained with TACSTD2 Recombinant Mouse Monoclonal Antibody (rTACSTD2/6395).
	Formalin-fixed, paraffin-embedded human liver in colon carcinoma stained with TACSTD2 Recombinant Mouse Monoclonal Antibody (rTACSTD2/6395).
	IHC analysis of formalin-fixed, paraffin-embedded human brain. Negative tissue control using rTACSTD2/6395 at 2ug/ml in PBS for 30min RT. HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
	SDS-PAGE Analysis of Purified TACSTD2 Recombinant Mouse Monoclonal (rTACSTD2/6395). Confirmation of Purity and Integrity of Antibody.
	Western blot analysis of Human skin and A-431 lysates using TACSTD2 / TROP2 (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (rTACSTD2/6395).
	Western blot analysis of Human skin, Mouse skin, Rat skin, Hamster skin, Guinea pig skin and Rabbit skin tissue lysates using TACSTD2 / TROP2 (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (rTACSTD2/6395).
	Western blot analysis of A-431 and MCF7 cell lysates using TACSTD2 / TROP2 (Epithelial Marker) Mouse Recombinant Monoclonal Antibody (rTACSTD2/6395).