DAUDI6, H2RIIBP, MGC1831, MHC class I promoter binding protein, NR2B2, nuclear receptor subfamily 2 group B member 2, RCoR1, Retinoic acid receptor RXR beta, RXR beta
Two families of retinoid receptors, RARs and RXRs, have been identified. Retinoic acid receptors (RARs) include RAR(TM), RARA°a and RARA, each of which have a high affinity for all trans-retinoic acids and belong to the same class of nuclear transcription factors as thyroid hormone receptors, vitamin D3 receptor and ecdysone receptor. The ligand-binding domains of the RARs are highly conserved and RAR isoforms are expressed in distinct patterns throughout development and in the mature organism. Members of the retinoid X receptor (RXR) family, RXR(TM), RXRA°a and RXRA, are activated by 9-cis-RA, a stereo- and photo-isomer of all trans-RA that is expressed in vivo in both liver and kidney and may represent a widely used hormone. As is true for the RAR subfamily, the RXR receptors are closely related to each other both in their DNA-binding and ligand-binding domains and are encoded by separate genes at distinct chromosomal loci.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human lymph node stained with RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6).
Immunofluorescence Analysis of PFA-fixed HeLa cells using RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6) followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).
Immunofluorescence Analysis of PFA-fixed K562 cells using RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6) followed by goat anti-mouse IgG-CF488 (green). CF640A phalloidin (red).
Flow Cytometric Analysis of PFA-fixed U87 cells. RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).
Flow Cytometric Analysis of PFA-fixed HeLa cells. RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6) followed by goat anti-mouse IgG-CF488 (blue), unstained cells (red).
Analysis of Protein Array containing more than 19,000 full-length human proteins using RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
SDS-PAGE Analysis. Purified RXRB Mouse Monoclonal Antibody (PCRP-RXRB-2B6). Confirmation of Purity and Integrity of Antibody.
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