Recombinant fragment (around aa 59-178) of human CD48 protein (exact sequence is proprietary)
Alternative Names:
B-cell activation marker, B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, BLAST1, CD48 antigen (B cell membrane protein), Signaling lymphocytic activation molecule 2 (SLAMF2), SLAM family member 2
Reacts with human CD48, a 45kDa glycosyl phophatidyl-inositol (GPI)-anchored cell surface protein. CD48 is strongly expressed on lymphocytes and monocytes and weakly on granulocytes but is absent on platelets, fibroblasts, epithelium and endothelium. CD48 is one of marker for detecting the defects of GPI anchoring structure on the patients with paroxysmal nocturnal hemoglobulinuria (PNH) and serves as a low affinity ligand for CD2.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Recombinant Monoclonal Antibody
Application Notes:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes),Optimal dilutio
SDS-PAGE Analysis of Purified CD48 Recombinant Rabbit Monoclonal Antibody (CD48/8360R). Confirmation of Purity and Integrity of Antibody.
Western blot analysis of Raji cell lysate using CD48 Recombinant Rabbit Monoclonal Antibody (CD48/8360R).
Formalin-fixed, paraffin-embedded human tonsil stained with CD48 Recombinant Rabbit Monoclonal Antibody (CD48/8360R). Inset: PBS instead of primary antibody, secondary only negative control.
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