Hydroxymethyl dasatinib (M24) is a benzylhydroxy metabolite of dasatinib that demonstrates potent antiproliferative activity with an IC50 value of 46.7 nM in K562 chronic myeloid leukemia cells, and is used in kinase inhibitor metabolism studies, structure-activity relationship analysis, and evaluation of active drug metabolites in leukemia research.
Molecular Weight:
504.01
CAS Number:
[910297-58-4]
Formula:
C22H26ClN7O3S
Target:
Bcr-Abl
T86695
T86695
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