Influenza A, Avian, H5N1, CT, Neuraminidase (NA) Control Peptide (Bird Flu)
Biozol Catalog Number:
USB-I7649-49A
Supplier Catalog Number:
I7649-49A
Alternative Catalog Number:
USB-I7649-49A-50
Manufacturer:
US Biological
Category:
Molekularbiologie
Application:
ELISA, WB
Influenza A virus is a major public health threat, killing more than 30,000 people per year in the USA. Novel influenza virus strains emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. Although it has been known that cleavage site and glycosylation patterns of the HA protein play important roles in determining the pathogenicity of H5 avian influenza viruses, it has only recently been shown that an additional glycosylation site within the globular head of the NA protein also contributes to the high virulence of the H5N1 virus. Control peptide for I7649-49 Synthetic peptide corresponding to15aa near the carboxy terminus of Avian influenza A (H5N1) neuraminidase (1). Applications: Suitable for use in Antibody Blocking. Other applications not tested. Recommended Dilution: Preadsorption Control: 1ug peptide per 1ug antibody for 30 min at 37C. Optimal dilutions to be determined by researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20C. Aliquots are stable for 6 months after receipt at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
Purified
Form:
Supplied as a liquid in PBS, pH 7.2, 0.1% BSA, 0.02% sodium azide.
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