Survivin (BIRC5, API4, EPR-1, baculoviral IAP repeat-containing 5 (survivin), survivin, apoptosis inhibitor 4), Goat
Catalog Number:
USB-S8500-06N
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| Article Name: | Survivin (BIRC5, API4, EPR-1, baculoviral IAP repeat-containing 5 (survivin), survivin, apoptosis inhibitor 4), Goat |
| Biozol Catalog Number: | USB-S8500-06N |
| Supplier Catalog Number: | S8500-06N |
| Alternative Catalog Number: | USB-S8500-06N-100 |
| Manufacturer: | US Biological |
| Host: | Goat |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Immunogen: | Synthetic peptide corresponding to CVRRAIEQLAAMD from the C-terminal region of human Survivin |
| Survivin, otherwise known as TIAP/BIRC5, is a novel inhibitor of apoptosis (IAP) protein, and component of the chromosomal passenger complex, which plays a key role in the regulation of mitosis. Survivin is only expressed during the G2-M cell cycle phase, and is predominantly expressed in fetal tissues, and in many human cancers, including adenocarcinomas and high-grade lymphomas. The lack of survivin expression by normal non-malignant cells, makes survivin an important therapeutic target for cancer. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Peptide ELISA: 1:16,000 Western Blot: 0.01-0.5ug/ml, detects a band of ~18kD in MOLT4 cell lysates. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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