Synphilin 1 (Synphilin-1, SYPH1, Alpha Synuclein-interacting Protein, MGC39814, Synuclein alpha Interacting Protein (Synphilin), SNCAIP) (Not for Export EU), Rabbit
Biozol Catalog Number:
USB-S9116-01
Supplier Catalog Number:
S9116-01
Alternative Catalog Number:
USB-S9116-01-100
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
IHC
Immunogen:
A synthetic peptide (SL ELNGEKDKDK GRTLQRT) as part of human synphilin-1a conjugated to KLH.
Synuclein alpha interacting protein (Synphilin-1) contains several protein-protein interaction domains and interacts with alpha synuclein in neurons. Mutations of SNCAIP have been linked to Parkinson disease. The amino acid sequence of synphilin-1 shares a high level of identity with its human counterpart, particularly in regions containing ankyrin-like motifs and the coiled-coil domain. Expression pattern of synphilin-1 in tissues is similar in both mouse and human. Synphilin-1 has an important role in the formation of aggregates and cytotoxicity in Parkinson disease and also Dorfin may be involved in the pathogenic process by ubiquitylation of synphilin-1. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20C. Aliquots are stable for at least 12 months at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Purity:
Serum
Form:
Supplied as a lyophilized powder. Reconstitute in 100ul of sterile water. Centrifuge to remove any insoluble material.
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