TACI (Transmembrane Activator and CAML Interactor, CD267), Rabbit
Biozol Catalog Number:
USB-T0294-06
Supplier Catalog Number:
T0294-06
Alternative Catalog Number:
USB-T0294-06-100
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
WB
Immunogen:
Synthetic peptide corresponding to a region within the N-terminus of human TACI.
Members in the TNF superfamily regulate immune responses and induce apoptosis. Two novel members in the TNF family were recently identified and designated BAFF/BLyS/TALL-1/THANK/zTNF4 (1-4) and April/TALL- 2, respectively, (3,5). BAFF was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion (1,2). April regulates immunological and non-immunological cell growth. Three receptors, BCMA, TACI, and BAFF-R, for BAFF and April were recently identified (6,7). TACI, like BCMA, binds BAFF and April. TACI and its ligands regulate humoral immune responses, activate NF-kB and c-jun N-terminal kinase, and are involved in B cell associated autoimmune diseases. SOURCE: Rabbit anti-TACI polyclonal antibody was raised against a synthetic peptide mapping at the amino terminus of human TACI (8). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 2-5ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Purity:
Purified by immunoaffinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.
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