Taste Receptor 2 (TR2) (Not for Export EU), Rabbit
Biozol Catalog Number:
USB-T1024-03A
Supplier Catalog Number:
T1024-03A
Alternative Catalog Number:
USB-T1024-03A-100
Manufacturer:
US Biological
Host:
Rabbit
Category:
Antikörper
Application:
ELISA
Immunogen:
A 19aa peptide sequence near the C-terminus of rat TR2 conjugated to KLH. Species sequence homology: mouse, 100%, human, 88%.
Higher vertebrates are believed to possess at least five basic tastes: Sweet, bitter, sour, salty, and unami (the taste of monosodium glutamate). Taste receptor cells that may selectively reside in various parts of the tongue and respond to different tastants and perceive these taste modalities. Circumvallate papillae, found at the very back of the tongue, are particularly sensitive to biter substances. Foliate papillae, found at the posterior lateral edge of the tongue, are sensitive to sour and bitter. Fungiform papillae at the front of the tongue specialize in sweet taste. Recently, two novel taste receptors, TR1 and TR2, have been cloned with distinct topographical distribution in taste receptor cells and taste buds. TRs are members of a new group of 7 TM domain containing GPCR distantly related to other chemosensory receptors (Ca+-sensing receptor (CaSR, a family of putative hormone receptor (V2R), and metabotropic glutamate receptors). TR1 is expressed in all fungiform taste buds, whereas TR2 localized to the circumvallate taste buds. Both receptors do not colocalize with gustducin. Applications: Suitable for use in ELISA. Western Blot, though not tested, may potentially be used as an application. Other applications not tested. Recommended Dilution: ELISA: 1:10,000-50,000. Control peptide can be used to coat ELISA plates at 1ug/ml. Optimal dilutions to be determined by the researcher. Control Peptide: T1024-03 Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Purity:
Serum
Form:
Supplied as a liquid, in 0.05% azide.
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