The T Cell Receptor alpha/beta (TCR) is expressed on T lymphocytes of all mouse strains tested. Plate-bound or soluble antibody activates a/b TCR-bearing T cells. In vitro and in vivo, the antibody can induce immature thymocytes to undergo apoptosis. In vivo administration of this antibody has been shown to deplete a/b TCR-bearing cells to near completion and prevent graft rejection. Recommended Secondary Antibody: Goat anti Hamster IgG: RPE Fusion Partners: Spleen cells from immunized armenian hamsters were fused with cells of the mouse P3X63Ag.653 myeloma cell line. Recommended Negative Controls: Hamster IgG Negative Control Applications: Flow Cytometry: 0.2-1ug/10e6 cells Immunoprecipitation Optimal working dilutions to be determined by researcher. Note: Applications are based on unconjugated antibody.
Clonality:
Monoclonal
Clone Designation:
[H57-597]
Purity:
Purified by Protein A affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2. Labeled with R-Phycoerythrin (PE).
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