TSPAN8 (Tetraspanin 8, CO-029, TM4SF3, Transmembrane 4 Superfamily Member 3, Tumor-Associated Antigen CO-029) (PE), IgG2b, Clone: [11n186], Rat, Monoclonal
Biozol Catalog Number:
USB-T3300-01A
Supplier Catalog Number:
T3300-01A
Alternative Catalog Number:
USB-T3300-01A-100
Manufacturer:
US Biological
Host:
Rat
Category:
Antikörper
Application:
FC
Immunogen:
CHO Chinese hamster ovary cell line transfected with mouse TSPAN8.
Tetraspanin-8 (TSPAN8), is a member of the transmembrane 4 superfamily. It is a cell surface 27-34kD protein with 4 transmembrane segments, and a large extracellular loop (LEL) domain from aa106-206. Both the N- and C-termini are intracellular. The protein is involved in cell motility, metastasis, cell proliferation and differentiation, and is over-expressed in different carcinomas including hepatocellular carcinoma and colon cancer. Human Tetraspanin-8 shares 70aa sequence identity with both mouse and rat TSPAN8. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry: 10ul labels 10e6 cells in CMT-93 mouse cell line Optimal dilutions to be determined by the researcher. Absorption: 488nm Emission: 565-605nm Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
