TGIF, ID (L223) (Homeobox Protein TGIF1, 5-TG-3-interacting Factor 1, TGIF1), Rabbit
Catalog Number:
USB-T3630-01D
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| Article Name: | TGIF, ID (L223) (Homeobox Protein TGIF1, 5-TG-3-interacting Factor 1, TGIF1), Rabbit |
| Biozol Catalog Number: | USB-T3630-01D |
| Supplier Catalog Number: | T3630-01D |
| Alternative Catalog Number: | USB-T3630-01D-200 |
| Manufacturer: | US Biological |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Immunogen: | Synthetic peptide selected from the Center region of human TGIF1 (KLH). |
| TGIF1 is a member of the threeaa loop extension (TALE) superclass of atypical homeodomains. TALE homeobox proteins are highly conserved transcription regulators. This particular homeodomain binds to a previously characterized retinoid X receptor responsive element from the cellular retinol-binding protein II promoter. In addition to its role in inhibiting 9-cis-retinoic acid-dependent RXR alpha transcription activation of the retinoic acid responsive element, the protein is an active transcriptional co-repressor of SMAD2 and may participate in the transmission of nuclear signals during development and in the adult. Mutations in this gene are associated with holoprosencephaly type 4, which is a structural anomaly of the brain. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. |
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