Tim3 (T Cell Immunoglobulin and Mucin Domain Containing Protein 3, Hepatitis Virus Cellular Receptor 2, CD366) (PE), Clone: [F38-2E2], Mouse, Monoclonal
Catalog Number:
USB-T5469-92Q
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| Article Name: | Tim3 (T Cell Immunoglobulin and Mucin Domain Containing Protein 3, Hepatitis Virus Cellular Receptor 2, CD366) (PE), Clone: [F38-2E2], Mouse, Monoclonal |
| Biozol Catalog Number: | USB-T5469-92Q |
| Supplier Catalog Number: | T5469-92Q |
| Alternative Catalog Number: | USB-T5469-92Q-25,USB-T5469-92Q-100 |
| Manufacturer: | US Biological |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC |
| Immunogen: | Human Tim-3 fusion protein |
| CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 5ul/10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C in the dark. DO NOT FREEZE! Stable at 4C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. |
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