Tissue Inhibitor of Metalloproteinases 2 (TIMP2), Clone: [2Q762 67-4H11], Mouse, Monoclonal

Catalog Number: USB-T5585-27
Article Name: Tissue Inhibitor of Metalloproteinases 2 (TIMP2), Clone: [2Q762 67-4H11], Mouse, Monoclonal
Biozol Catalog Number: USB-T5585-27
Supplier Catalog Number: T5585-27
Alternative Catalog Number: USB-T5585-27-100
Manufacturer: US Biological
Host: Mouse
Category: Antikörper
Application: ELISA, IHC, WB
Immunogen: Synthetic peptide corresponding to aa178-193, YRGAAPPKQEFLDIED of human TIMP-2.
TIMP-2 is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kD Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kD Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Applications: Suitable for use in Western Blot, ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Immunohistochemistry (PLP fixed tissue): 5ug/ml Immunohistochemistry (Frozen): 1ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality: Monoclonal
Clone Designation: [2Q762 67-4H11]
NCBI: 003255
UniProt: P16035
Purity: Purified.
Form: Supplied as a liquid in 0.1M PBS, pH 7.0, 2% BSA (Protease free).