TLR4/MD-2 Complex (Toll Like Receptor 4/MD-2, MD-2, Toll Like Receptor 4, TLR4) (Biotin), Clone: [MTS510], Rat, Monoclonal
Biozol Catalog Number:
USB-T8050-35C1
Supplier Catalog Number:
T8050-35C1
Alternative Catalog Number:
USB-T8050-35C1-50
Manufacturer:
US Biological
Host:
Rat
Category:
Antikörper
Application:
FC
Immunogen:
Ba/F3 cell line transfected with mouse TLR4 /MD2 complex
Toll-like receptors (TLR) are highly conserved throughout evolution and have been implicated in the innate defense to many pathogens. In Drosophila toll is required for the anti-fungal response, while the related 18-wheeler is involved in antibacterial defenses. In mammals, TLR identified as type I transmembrane signaling receptors with pattern recognition capabilities, have been implicated in the innate host defense to pathogens. TLR4 has been identified next to MD-2 and CD14 as a receptor that is central to the innate immune response to lipopolysaccharides (LPS) of Gram-negative bacteria. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilutions: Flow Cytometry: 0.25ug/10e6 cells in 100ul Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20C. Aliquots are stable at -20C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clonality:
Monoclonal
Clone Designation:
[MTS510]
Purity:
Purified by affinity chromatography.
Form:
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Labeled with Biotin.
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