Synthetic peptide corresponding to aa1-8 (FKTLRTIA) circulating form of human Uroguanylin
Uroguanylin is a 16aa peptide that is secreted by enterochromaffin cells in the duodenum and proximal small intestine. Guanylin acts as an agonist of the guanylyl cyclase receptor GC-C and regulates electrolyte and water transport in intestinal and renal epithelia. Applications: Suitable for use in ELISA, Immunohistochemistry, Western Blot and RIA. Other applications not tested. Recommended Dilutions: ELISA: 1:2000 Immunohistochemistry (Acrylic resin): 1:800 Western Blot: 1:1000 RIA: 1:10,000 Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized and reconstituted products are stable for 12 months after receipt at -20C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
