KIF7 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A15581
- Bilder (1)
| Artikelname: | KIF7 Rabbit pAb, Unconjugated, Polyclonal |
| Artikelnummer: | ABB-A15581 |
| Hersteller Artikelnummer: | A15581 |
| Alternativnummer: | ABB-A15581-100UL,ABB-A15581-20UL,ABB-A15581-1000UL,ABB-A15581-500UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | ACLS, AGBK, HLS2, MMEDF, JBTS12, UNQ340, KIF7 |
| This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. |
| Klonalität: | Polyclonal |
| Molekulargewicht: | 151kDa |
| NCBI: | 374654 |
| UniProt: | Q2M1P5 |
| Reinheit: | Affinity purification |
| Sequenz: | QLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPRTREETRDLVHAPLPLTWKRSSLCGEEQGSPEELRQREA |
| Target-Kategorie: | KIF7 |
| Antibody Type: | Primary Antibody |
| Application Verdünnung: | WB,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human. ResearchArea: Cytoskeleton,Motor Proteins,Stem Cells. Shipping: Ice Bag |
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Western blot analysis of various lysates using KIF7 Rabbit pAb (A15581) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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