KIF7 Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A15581
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| Article Name: | KIF7 Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A15581 |
| Supplier Catalog Number: | A15581 |
| Alternative Catalog Number: | ABB-A15581-100UL,ABB-A15581-20UL,ABB-A15581-1000UL,ABB-A15581-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | ACLS, AGBK, HLS2, MMEDF, JBTS12, UNQ340, KIF7 |
| This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. |
| Clonality: | Polyclonal |
| Molecular Weight: | 151kDa |
| NCBI: | 374654 |
| UniProt: | Q2M1P5 |
| Purity: | Affinity purification |
| Sequence: | QLDEAIEALDAAIEYKNEAITCRQRVLRASASLLSQCEMNLMAKLSYLSSSETRALLCKYFDKVVTLREEQHQQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRDHLGEGLADSRRQYEARIQALEKELGRYMWINQELKQKLGGVNAVGHSRGGEKRSLCSEGRQAPGNEDELHLAPELLWLSPLTEGAPRTREETRDLVHAPLPLTWKRSSLCGEEQGSPEELRQREA |
| Target: | KIF7 |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:200 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human. ResearchArea: Cytoskeleton,Motor Proteins,Stem Cells. Shipping: Ice Bag |
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Western blot analysis of various lysates using KIF7 Rabbit pAb (A15581) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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