SCN5A Rabbit pAb, Unconjugated, Polyclonal

Artikelnummer: ABB-A16665
Artikelname: SCN5A Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer: ABB-A16665
Hersteller Artikelnummer: A16665
Alternativnummer: ABB-A16665-100UL,ABB-A16665-20UL,ABB-A16665-500UL,ABB-A16665-1000UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human
Immunogen: This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: HB1, HB2, HH1, IVF, VF1, HBBD, ICCD, LQT3, SSS1, CDCD2, CMD1E, CMPD2, PFHB1, Nav1.5, SCN5A
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene have been associated with long QT syndrome type 3 (LQT3), atrial fibrillation, cardiomyopathy, and Brugada syndrome 1, all autosomal dominant cardiac diseases. Alternative splicing results in several transcript variants encoding different isoforms.
Klonalität: Polyclonal
Molekulargewicht: 227 kDa
NCBI: 6331
UniProt: Q14524
Reinheit: Affinity purification
Sequenz: YVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV
Target-Kategorie: SCN5A
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Mouse. ResearchArea: Neuroscience,Cardiovascular,Heart,Cardiac arrhythmias. Shipping: Ice Bag
Western blot analysis of lysates from Mouse lung, using SCN5A Rabbit pAb (A16665) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 40s.