SCN5A Rabbit pAb, Unconjugated, Polyclonal

Catalog Number: ABB-A16665
Article Name: SCN5A Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number: ABB-A16665
Supplier Catalog Number: A16665
Alternative Catalog Number: ABB-A16665-100UL,ABB-A16665-20UL,ABB-A16665-500UL,ABB-A16665-1000UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: HB1, HB2, HH1, IVF, VF1, HBBD, ICCD, LQT3, SSS1, CDCD2, CMD1E, CMPD2, PFHB1, Nav1.5, SCN5A
The protein encoded by this gene is an integral membrane protein and tetrodotoxin-resistant voltage-gated sodium channel subunit. This protein is found primarily in cardiac muscle and is responsible for the initial upstroke of the action potential in an electrocardiogram. Defects in this gene have been associated with long QT syndrome type 3 (LQT3), atrial fibrillation, cardiomyopathy, and Brugada syndrome 1, all autosomal dominant cardiac diseases. Alternative splicing results in several transcript variants encoding different isoforms.
Clonality: Polyclonal
Molecular Weight: 227 kDa
NCBI: 6331
UniProt: Q14524
Purity: Affinity purification
Sequence: YVMSENFSRPLGPPSSSSISSTSFPPSYDSVTRATSDNLQVRGSDYSHSEDLADFPPSPDRDRESIV
Target: SCN5A
Antibody Type: Primary Antibody
Application Dilute: WB,1:500 - 1:5000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Mouse. ResearchArea: Neuroscience,Cardiovascular,Heart,Cardiac arrhythmias. Shipping: Ice Bag
Western blot analysis of lysates from Mouse lung, using SCN5A Rabbit pAb (A16665) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 40s.