PTGDS Rabbit pAb, Unconjugated, Polyclonal

Artikelnummer: ABB-A1889
Artikelname: PTGDS Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer: ABB-A1889
Hersteller Artikelnummer: A1889
Alternativnummer: ABB-A1889-100UL,ABB-A1889-20UL,ABB-A1889-1000UL,ABB-A1889-500UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IF, WB
Spezies Reaktivität: Human
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS, PTGDS
The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep.
Klonalität: Polyclonal
Molekulargewicht: 21kDa
NCBI: 5730
UniProt: P41222
Reinheit: Affinity purification
Sequenz: APEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ
Target-Kategorie: PTGDS
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:100 - 1:500|IF/ICC,1:50 - 1:100|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction. Shipping: Ice Bag
Western blot analysis of lysates from Mouse heart, using PTGDS Rabbit pAb (A1889) at 1:500 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180s.