PTGDS Rabbit pAb, Unconjugated, Polyclonal
Catalog Number:
ABB-A1889
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| Article Name: | PTGDS Rabbit pAb, Unconjugated, Polyclonal |
| Biozol Catalog Number: | ABB-A1889 |
| Supplier Catalog Number: | A1889 |
| Alternative Catalog Number: | ABB-A1889-100UL,ABB-A1889-20UL,ABB-A1889-1000UL,ABB-A1889-500UL |
| Manufacturer: | ABclonal |
| Host: | Rabbit |
| Category: | Antikörper |
| Application: | ELISA, IF, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Conjugation: | Unconjugated |
| Alternative Names: | PDS, PGD2, PGDS, LPGDS, PGDS2, L-PGDS, PTGDS |
| The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. |
| Clonality: | Polyclonal |
| Molecular Weight: | 21kDa |
| NCBI: | 5730 |
| UniProt: | P41222 |
| Purity: | Affinity purification |
| Sequence: | APEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKKAALSMCKSVVAPATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSVSVVETDYDQYALLYSQGSKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTIVFLPQTDKCMTEQ |
| Target: | PTGDS |
| Antibody Type: | Primary Antibody |
| Application Dilute: | WB,1:100 - 1:500|IF/ICC,1:50 - 1:100|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Application Notes: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Signal Transduction. Shipping: Ice Bag |
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Western blot analysis of lysates from Mouse heart, using PTGDS Rabbit pAb (A1889) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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