WRAP53 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A20167
- Bilder (1)
| Artikelname: | WRAP53 Rabbit pAb, Unconjugated, Polyclonal |
| Artikelnummer: | ABB-A20167 |
| Hersteller Artikelnummer: | A20167 |
| Alternativnummer: | ABB-A20167-100UL,ABB-A20167-20UL,ABB-A20167-1000UL,ABB-A20167-500UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | DKCB3, TCAB1, WDR79, WRAP53 |
| This gene encodes an essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex required for telomere synthesis. This protein is enriched in Cajal bodies, nuclear sites of RNP processing that are important for telomerase function. It interacts with dyskerin, TERT and TERC, other components of active telomerase, and with small Cajal body RNAs (scaRNAs), which are involved in modifying splicing RNAs. This mRNA also functions as a p53 antisense transcript, that regulates endogenous p53 mRNA levels and further induction of p53 protein by targeting the 5 untranslated region of p53 mRNA. Alternatively spliced transcript variants which differ only in the 5 UTR have been found for this gene. |
| Application Verdünnung: | WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Mouse. ResearchArea: Cell Biology Developmental Biology. Shipping: Ice Bag |
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Western blot analysis of lysates from Mouse kidney, using WRAP53 Rabbit pAb (A20167) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180s. |
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