Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation:
Unconjugated
Symmetric Dimethylarginine is a dimethylated derivative of L-arginine where the two methyl groups are attached to arginine in a symmetrical configuration. Symmetric dimethylarginine (SDMA) is formed when S-adenosylmethionine protein N-methyltransferases transfer one methyl group from S-adenosylmethionine to each of the two guanidine nitrogen groups of a single arginine residue in a protein. SDMA is released when the protein is degraded. SDMA doesnt bind nitric oxide synthase (NOS) but may noncompetitivelty inhibit nitric oxide (NO) synthesis by reducing L-arginine availability, it also may play a role in the modulation of cardiovascular homeostasis and renal function.
Klonalität:
Monoclonal
Klon-Bezeichnung:
[ARC51197]
Reinheit:
Affinity purification
Target-Kategorie:
Pan-Symmetric Di-Methyl Arginine Motif
Antibody Type:
Primary Antibody
Application Verdünnung:
WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung:
Cross-Reactivity: Human,Mouse,Rat,Other (Wide Range Predicted). Shipping: Ice Bag
Western blot analysis of various lysates using Pan-Symmetric Di-Methyl Arginine Motif Rabbit mAb (A20794) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 180 s.
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten