Pan-Symmetric Di-Methyl Arginine Motif Rabbit mAb, Unconjugated

Catalog Number: ABB-A20794
Article Name: Pan-Symmetric Di-Methyl Arginine Motif Rabbit mAb, Unconjugated
Biozol Catalog Number: ABB-A20794
Supplier Catalog Number: A20794
Alternative Catalog Number: ABB-A20794-100UL,ABB-A20794-20UL,ABB-A20794-500UL,ABB-A20794-1000UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Symmetric Dimethylarginine is a dimethylated derivative of L-arginine where the two methyl groups are attached to arginine in a symmetrical configuration. Symmetric dimethylarginine (SDMA) is formed when S-adenosylmethionine protein N-methyltransferases transfer one methyl group from S-adenosylmethionine to each of the two guanidine nitrogen groups of a single arginine residue in a protein. SDMA is released when the protein is degraded. SDMA doesnt bind nitric oxide synthase (NOS) but may noncompetitivelty inhibit nitric oxide (NO) synthesis by reducing L-arginine availability, it also may play a role in the modulation of cardiovascular homeostasis and renal function.
Clonality: Monoclonal
Clone Designation: [ARC51197]
Purity: Affinity purification
Target: Pan-Symmetric Di-Methyl Arginine Motif
Antibody Type: Primary Antibody
Application Dilute: WB,1:1000 - 1:2000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat,Other (Wide Range Predicted). Shipping: Ice Bag
Western blot analysis of various lysates using Pan-Symmetric Di-Methyl Arginine Motif Rabbit mAb (A20794) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25 µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 180 s.