TRIM24 Rabbit mAb, Unconjugated, Monoclonal

Artikelnummer: ABB-A20938
Artikelname: TRIM24 Rabbit mAb, Unconjugated, Monoclonal
Artikelnummer: ABB-A20938
Hersteller Artikelnummer: A20938
Alternativnummer: ABB-A20938-100UL,ABB-A20938-20UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA, TRIM24
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Klonalität: Monoclonal
Molekulargewicht: 117kDa
NCBI: 8805
UniProt: O15164
Reinheit: Affinity purification
Target-Kategorie: TRIM24
Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,MAPK-Erk Signaling Pathway. Shipping: Ice Bag
Western blot analysis of various lysates using TRIM24 Rabbit mAb (A20938) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.