TRIM24 Rabbit mAb, Unconjugated, Monoclonal

Catalog Number: ABB-A20938
Article Name: TRIM24 Rabbit mAb, Unconjugated, Monoclonal
Biozol Catalog Number: ABB-A20938
Supplier Catalog Number: A20938
Alternative Catalog Number: ABB-A20938-100UL,ABB-A20938-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Human
Immunogen: Synthetic peptide. This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: PTC6, TF1A, TIF1, RNF82, TIF1A, hTIF1, TIF1ALPHA, TRIM24
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Clonality: Monoclonal
Molecular Weight: 117kDa
NCBI: 8805
UniProt: O15164
Purity: Affinity purification
Target: TRIM24
Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,Nuclear Receptor Signaling,Nuclear hormone receptors,Signal Transduction,MAPK-Erk Signaling Pathway. Shipping: Ice Bag
Western blot analysis of various lysates using TRIM24 Rabbit mAb (A20938) at 1:1000 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 60s.