CHD3 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer:
ABB-A2221
- Bilder (1)
| Artikelname: | CHD3 Rabbit pAb, Unconjugated, Polyclonal |
| Artikelnummer: | ABB-A2221 |
| Hersteller Artikelnummer: | A2221 |
| Alternativnummer: | ABB-A2221-100UL,ABB-A2221-20UL,ABB-A2221-1000UL,ABB-A2221-500UL |
| Hersteller: | ABclonal |
| Wirt: | Rabbit |
| Kategorie: | Antikörper |
| Applikation: | ELISA, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | Synthetic peptide. This information is considered to be commercially sensitive. |
| Konjugation: | Unconjugated |
| Alternative Synonym: | ZFH, Mi-2a, SNIBCPS, Mi2-ALPHA, CHD3 |
| This gene encodes a member of the CHD family of proteins which are characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. This protein is one of the components of a histone deacetylase complex referred to as the Mi-2/NuRD complex which participates in the remodeling of chromatin by deacetylating histones. Chromatin remodeling is essential for many processes including transcription. Autoantibodies against this protein are found in a subset of patients with dermatomyositis. Three alternatively spliced transcripts encoding different isoforms have been described. |
| Application Verdünnung: | WB,1:200 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements. |
| Anwendungsbeschreibung: | Cross-Reactivity: Human,Mouse,Rat. ResearchArea: Epigenetics Nuclear Signaling,RNA Binding,Chromatin Remodeling,Immunology Inflammation. Shipping: Ice Bag |
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Western blot analysis of various lysates using CHD3 Rabbit pAb (A2221) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution. Lysates/proteins: 25µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (RM00021). Exposure time: 30s. |
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