JAM-A/CD321 Rabbit pAb, Unconjugated, Polyclonal

Artikelnummer: ABB-A23909
Artikelname: JAM-A/CD321 Rabbit pAb, Unconjugated, Polyclonal
Artikelnummer: ABB-A23909
Hersteller Artikelnummer: A23909
Alternativnummer: ABB-A23909-500UL,ABB-A23909-1000UL,ABB-A23909-100UL,ABB-A23909-20UL
Hersteller: ABclonal
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, WB
Spezies Reaktivität: Mouse
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Konjugation: Unconjugated
Alternative Synonym: JAM, Jcam, JAM-1, JAM-A, Jcam1, Ly106, ESTM33, 9130004G24, JAM-A/CD321
Predicted to enable PDZ domain binding activity, integrin binding activity, and protein homodimerization activity. Involved in intestinal absorption, regulation of cytokine production, and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo, alimentary system, respiratory system, sensory organ, and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).
Klonalität: Polyclonal
Molekulargewicht: 32kDa
NCBI: 16456
UniProt: Q92993
Reinheit: Affinity purification
Sequenz: KGSVYTAQSDVQVPENESIKLTCTYSGFSSPRVEWKFVQGSTTALVCYNSQITAPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEEGGQNYGEVSIHLTVLVPPSKPTISVPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGISMLTADAKKTRAFMNSSFTIDPKSGDLIFDPVTAFDSGEYYCQAQNGYGTAMRSEAAHMDAVELNVGGIVAA
Target-Kategorie: CD321
Antibody Type: Primary Antibody
Application Verdünnung: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Anwendungsbeschreibung: Cross-Reactivity: Human,Mouse,Rat. Shipping: Ice Bag
Western blot analysis of lysates from A-431 cells, using JAM-A/CD321 Rabbit pAb (A23909) at 1:700 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.