JAM-A/CD321 Rabbit pAb, Unconjugated, Polyclonal

Catalog Number: ABB-A23909
Article Name: JAM-A/CD321 Rabbit pAb, Unconjugated, Polyclonal
Biozol Catalog Number: ABB-A23909
Supplier Catalog Number: A23909
Alternative Catalog Number: ABB-A23909-500UL,ABB-A23909-1000UL,ABB-A23909-100UL,ABB-A23909-20UL
Manufacturer: ABclonal
Host: Rabbit
Category: Antikörper
Application: ELISA, WB
Species Reactivity: Mouse
Immunogen: Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Conjugation: Unconjugated
Alternative Names: JAM, Jcam, JAM-1, JAM-A, Jcam1, Ly106, ESTM33, 9130004G24, JAM-A/CD321
Predicted to enable PDZ domain binding activity, integrin binding activity, and protein homodimerization activity. Involved in intestinal absorption, regulation of cytokine production, and regulation of membrane permeability. Acts upstream of or within cell adhesion and epithelial cell differentiation. Located in bicellular tight junction. Is expressed in several structures, including 4-8 cell stage embryo, alimentary system, respiratory system, sensory organ, and urinary system. Human ortholog(s) of this gene implicated in hypertension. Orthologous to human F11R (F11 receptor).
Clonality: Polyclonal
Molecular Weight: 32kDa
NCBI: 16456
UniProt: Q92993
Purity: Affinity purification
Sequence: KGSVYTAQSDVQVPENESIKLTCTYSGFSSPRVEWKFVQGSTTALVCYNSQITAPYADRVTFSSSGITFSSVTRKDNGEYTCMVSEEGGQNYGEVSIHLTVLVPPSKPTISVPSSVTIGNRAVLTCSEHDGSPPSEYSWFKDGISMLTADAKKTRAFMNSSFTIDPKSGDLIFDPVTAFDSGEYYCQAQNGYGTAMRSEAAHMDAVELNVGGIVAA
Target: CD321
Antibody Type: Primary Antibody
Application Dilute: WB,1:500 - 1:1000|ELISA,Recommended starting concentration is 1 µg/mL. Please optimize the concentration based on your specific assay requirements.
Application Notes: Cross-Reactivity: Human,Mouse,Rat. Shipping: Ice Bag
Western blot analysis of lysates from A-431 cells, using JAM-A/CD321 Rabbit pAb (A23909) at 1:700 dilution.
Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25µg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 10s.