A partial length recombinant TOX-3 protein (amino acids 232-442) was used as the immunogen for this antibody
Alternative Synonym:
TOX3||CAGF9||TNRC9
TOX high mobility group box family member 3 (TOX-3) is a member of a subfamily of transcription factors that contains a High Mobility Group box (HMG-box), involved in bending and unwinding of DNA and alteration of chromatin structure. It has two transcript variants encoding different isoforms.TOX3 is expressed in estrogen receptor-positive mammary epithelial cells, including progenitor cells and highly expressed in luminal B breast cancers. Its over expression in human oligodendrocytes reduced cellular death under conditions mimicking Spinal cord injury (SCI).
Western blot analysis: 2-4 µg/ml, Immunohistochemical analysis: 5 µg/ml
Fig-1: Western blot analysis of TOX-3. Anti- TOX-3 antibody (Clone: ABM44A1) was tested at 2 µg/ml on (1) PC3, (2) h Testis, (3) HCT-116, (4) h Lung, (5) h Brain, (6) MCF-7 and (7) U87 lysates.
Fig-2 : Immunohistochemical analysis of TOX-3 in human stomach tissue using TOX-3 antibody (Clone: ABM44A1) at 5 µg/ml.
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