Monoclonal Antibody to Insulin / IRDN (beta-Cell & Insulinoma Marker)(E2-E3 + 2D11-H5, same as INS04 + INS05), Clone: [E2-E3 + 2D11-H5, same as INS04 + INS05], Mouse
Artikelnummer:
ABI-36-1312
Hersteller Artikelnummer:
36-1312
Alternativnummer:
ABI-36-1312-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human, Mouse
Immunogen:
Purified pig insulin, conjugated to KLH (E2-E3 & 2D11-H5)
Alternative Synonym:
INS
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Insulin / IRDN (beta-Cell & Insulinoma Marker)
Application Verdünnung:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
