Monoclonal Antibody to Insulin / IRDN (beta-Cell & Insulinoma Marker)(E2-E3 + 2D11-H5, same as INS04 + INS05), Clone: [E2-E3 + 2D11-H5, same as INS04 + INS05], Mouse
Biozol Catalog Number:
ABI-36-1312
Supplier Catalog Number:
36-1312
Alternative Catalog Number:
ABI-36-1312-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human, Mouse
Immunogen:
Purified pig insulin, conjugated to KLH (E2-E3 & 2D11-H5)
Alternative Names:
INS
Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Insulin / IRDN (beta-Cell & Insulinoma Marker)
Application Dilute:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),
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