Monoclonal Antibody to CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)(Clone : C117/370), Clone: [C117/370], Mouse
Artikelnummer:
ABI-36-1335
Hersteller Artikelnummer:
36-1335
Alternativnummer:
ABI-36-1335-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Recombinant human CD117 protein
Alternative Synonym:
KIT||SCFR
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposis sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)
Application Verdünnung:
Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA buffer, pH 9.5, for 45 min at 95&degC followed by cooling at RT for 20 minutes)
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