Monoclonal Antibody to CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)(Clone : C117/370), Clone: [C117/370], Mouse

Catalog Number: ABI-36-1335
Article Name: Monoclonal Antibody to CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)(Clone : C117/370), Clone: [C117/370], Mouse
Biozol Catalog Number: ABI-36-1335
Supplier Catalog Number: 36-1335
Alternative Catalog Number: ABI-36-1335-100UG
Manufacturer: Abeomics
Host: Mouse
Category: Antikörper
Application: IHC
Species Reactivity: Human
Immunogen: Recombinant human CD117 protein
Alternative Names: KIT||SCFR
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposis sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Clonality: Monoclonal
Clone Designation: [C117/370]
NCBI: 3815
UniProt: P10721
Purity: Affinity Chromatography
Form: Purified
Target: CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)
Application Dilute: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 1mM EDTA buffer, pH 9.5, for 45 min at 95&degC followed by cooling at RT for 20 minutes)