Monoclonal Antibody to CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)(Clone : KIT/983), Clone: [KIT/983], Mouse
Artikelnummer:
ABI-36-1337
Hersteller Artikelnummer:
36-1337
Alternativnummer:
ABI-36-1337-100UG
Hersteller:
Abeomics
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant human CD117 fragment around aa100-300
Alternative Synonym:
KIT||SCFR
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposis sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
