Monoclonal Antibody to CD117 / c-Kit (Marker for Gastrointestinal Stromal Tumors)(Clone : KIT/983), Clone: [KIT/983], Mouse
Biozol Catalog Number:
ABI-36-1337
Supplier Catalog Number:
36-1337
Alternative Catalog Number:
ABI-36-1337-100UG
Manufacturer:
Abeomics
Host:
Mouse
Category:
Antikörper
Application:
WB
Species Reactivity:
Human
Immunogen:
Recombinant human CD117 fragment around aa100-300
Alternative Names:
KIT||SCFR
This MAb recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposis sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
