CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide, Clone: [CB43], Mouse, Monoclonal

Artikelnummer: ABT-AH12366-U0100
Artikelname: CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide, Clone: [CB43], Mouse, Monoclonal
Artikelnummer: ABT-AH12366-U0100
Hersteller Artikelnummer: AH12366-U0100
Alternativnummer: ABT-AH12366-U0100-100UG
Hersteller: Abcepta
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF
Spezies Reaktivität: Human
Alternative Synonym: Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG
CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis.
Klonalität: Monoclonal
Klon-Bezeichnung: [CB43]
NCBI: 682
UniProt: P35613
Antibody Type: Monoclonal Antibody