CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide, Clone: [CB43], Mouse, Monoclonal
Catalog Number:
ABT-AH12366-U0100
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| Article Name: | CD147 / EMMPRIN / Neurothelin Antibody - With BSA and Azide, Clone: [CB43], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH12366-U0100 |
| Supplier Catalog Number: | AH12366-U0100 |
| Alternative Catalog Number: | ABT-AH12366-U0100-100UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF |
| Species Reactivity: | Human |
| Alternative Names: | Basigin, 5F7, Collagenase stimulatory factor, Extracellular matrix metalloproteinase inducer, EMMPRIN, Leukocyte activation antigen M6, OK blood group antigen, Tumor cell-derived collagenase stimulatory factor, TCSF, CD147, BSG |
| CD147 is a transmembrane glycoprotein of the immunoglobulin superfamily. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 is involved in the regulation of matrix remodeling at the epidermal-dermal interface. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes, which are typically increased during tissue degradation and wound healing, are important factors in cancer invasion and metastasis. |
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