CD282 (Toll-Like Receptor 2) Antibody - With BSA and Azide, Clone: [TLR2/221], Mouse, Monoclonal
Artikelnummer:
ABT-AH12424-U0020
Hersteller Artikelnummer:
AH12424-U0020
Alternativnummer:
ABT-AH12424-U0020-20UG
Hersteller:
Abcepta
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
FC, IF, IHC
Spezies Reaktivität:
Drosophila, Human
Alternative Synonym:
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Ā