CD282 (Toll-Like Receptor 2) Antibody - With BSA and Azide, Clone: [TLR2/221], Mouse, Monoclonal
Biozol Catalog Number:
ABT-AH12424-U0020
Supplier Catalog Number:
AH12424-U0020
Alternative Catalog Number:
ABT-AH12424-U0020-20UG
Manufacturer:
Abcepta
Host:
Mouse
Category:
Antikörper
Application:
FC, IF, IHC
Species Reactivity:
Drosophila, Human
Alternative Names:
Toll-like receptor 2, Toll/interleukin-1 receptor-like protein 4, CD282, TLR2, TIL4
This MAb reacts with human Toll-like receptor 2 (TLR2). It is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB.Ā