Anti-Catenin, alpha-1 (CTNNA1) Antibody, Clone: [1G5], Mouse, Monoclonal
Artikelnummer:
ABT-AH13141-U0100
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| Artikelname: | Anti-Catenin, alpha-1 (CTNNA1) Antibody, Clone: [1G5], Mouse, Monoclonal |
| Artikelnummer: | ABT-AH13141-U0100 |
| Hersteller Artikelnummer: | AH13141-U0100 |
| Alternativnummer: | ABT-AH13141-U0100-100UG |
| Hersteller: | Abcepta |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | FC, IF, WB |
| Spezies Reaktivität: | Human |
| Alternative Synonym: | Alpha E-catenin, Cadherin-associated protein, CAP102, Catenin alpha-1, CTNNA1, Renal carcinoma antigen NY-REN-13 |
| Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. |
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