Anti-Catenin, alpha-1 (CTNNA1) Antibody, Clone: [1G5], Mouse, Monoclonal
Catalog Number:
ABT-AH13141-U0100
- Images (0)
| Article Name: | Anti-Catenin, alpha-1 (CTNNA1) Antibody, Clone: [1G5], Mouse, Monoclonal |
| Biozol Catalog Number: | ABT-AH13141-U0100 |
| Supplier Catalog Number: | AH13141-U0100 |
| Alternative Catalog Number: | ABT-AH13141-U0100-100UG |
| Manufacturer: | Abcepta |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | FC, IF, WB |
| Species Reactivity: | Human |
| Alternative Names: | Alpha E-catenin, Cadherin-associated protein, CAP102, Catenin alpha-1, CTNNA1, Renal carcinoma antigen NY-REN-13 |
| Recognizes a protein of 102kDa, identified as Catenin, alpha-1. Catenins comprise a large family of Ca2+-dependent, homotypic cell-cell adhesion molecules that play important roles in development, epithelial cell polarity and tumor progression. Alpha-catenin is a key regulator of actin dynamics in cell-cell adhesion. During cell-cell adhesion, alpha-catenin forms a heterodimer with beta-catenin and links the cadherins to actin associated with the cytoskeleton. Alpha-catenin also regulates the beta-catenin signaling in various cells. It displays the tumor suppressor activity and is found to be down regulated in some forms of breast cancer. |
Product Guarantee and Expert Support
